Author links open overlay panel fernando valdes a carmen peteiro b jaime toribio b. Dowlingdegos disease ddd and reticulate acropigmentation of kitamura rak are rare genodermatoses inherited as an autosomal dominant trait with. Reticular pigmented anomaly of the flexures wikipedia. Dowlingdegos disease ddd is a rare genetic disease of the skin reticulate pigmented anomaly, clinically characterized by flexural brown pigmented. Dowling degos disease ddd is a rare genetic disease of the skin reticulate pigmented anomaly, clinically characterized by flexural brown pigmented reticulate macules, comedolike papules on the back, neck and pitted perioral or facial scars. May 23, 2019 dowling degos disease reticulate pigmented anomaly is slowly progressive. Dowlingdegos disease ddd is a rare reticular pigmentary disorder with an autosomal domi nant inheritance. Dowlingdegos disease ddd is a rare genetic disease of the skin reticulate pigmented anomaly, clinically characterized by flexural brown pigmented reticulate macules, comedolike papules on the back, neck and pitted perioral or facial scars. It is caused by a mutation in chromosome 17 that produces altered cytokeratins 5 and.
One of the patients daughters had similar reticulate pigmentation involving the axillae. Dowlingdegos disease with reticulate acropigmentation of. Over time comedolike lesions also appear on the back and neck, and perio. Reticular pigmented anomaly of the flexures also known as dark dot disease, and dowlingdegos disease is a fibrous anomaly of the flexures or bending parts of the axillae, neck and inframammarysternal areas 856 it is an autosomaldominant pigmentary disorder that may appear in adolescence or adulthood. It is characterized by pigmented filiform epidermal papules closely resembling an adenoid seborrheic keratosis, but similar proliferations also develop around the variably dilated pilosebaceous follicles. Abstract dowlingdegos disease has an autosomal dominant variable penetrance.
We present the case of a patient with pruritic hyperpigmentation of the chest and asymptomatic flexural hyperpigmentation. Dowling degos disease is a rare, reticulate pigmentary disorder with variable phenotypic. Dowling degos disease ddd is a rare autosomal dominant inherited pigmentary disorder of the flexures with a reticulate aspect and with presence of prominent comedonelike lesions and pitted scars. Dowlingdegos disease ddd is a rare autosomal dominant disorder, classically characterized by acquired reticular hyperpigmentation in. Degos disease annals of clinical and medical case reports. Dowlingdegos disease has an autosomal dominant variable penetrance. Dowlingdegos disease is an uncommon genodermatosis characterized by acquired, reticulated flexural hyperpigmentation.
1213 693 1304 1239 1084 650 1175 444 492 1577 300 99 1284 1161 1039 364 1438 950 145 612 1099 1226 1599 1218 778 1491 911 383 225 1203 982 627 268 1499 684 845 653 1494 684 130 123 573 1297 321 15